Version 5.4
| Homo sapiens Gene: MYCBP | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-235088.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | MYCBP | ||||||||||||||||||
| Gene Name | c-myc binding protein | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000214114 | ||||||||||||||||||
| Encoded Proteins |
c-myc binding protein
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This locus represents naturally occurring read-through transcription between the neighboring GJA9 (gap junction protein, alpha 9, 59kDa) and MYCBP (c-myc binding protein) genes on chromosome 1. Alternative splicing results in multiple transcript variants. These variants are either candidates for nonsense-mediated mRNA decay (NMD) and/or they lack a significant open reading frame, thus they are unlikely to produce protein products. [provided by RefSeq, Dec 2010] The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 1:38862964-38874495 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | p34.3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME | |||||||||||||||||||
| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI |
Notch signaling pathway
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| Cross-References | |||||||||||||||||||
| SwissProt | Q99417 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 26292 | ||||||||||||||||||
| UniGene | Hs.591506 Hs.622680 Hs.632402 | ||||||||||||||||||
| RefSeq | NM_012333 | ||||||||||||||||||
| HUGO | HGNC:7554 | ||||||||||||||||||
| OMIM | 606535 | ||||||||||||||||||
| CCDS | CCDS431 | ||||||||||||||||||
| HPRD | 08406 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AB007191 AB451287 AB451419 AK311886 AL139260 BC008686 BT007109 D50692 | ||||||||||||||||||
| GenPept | AAH08686 AAP35773 BAA09338 BAA22408 BAG34827 BAG70101 BAG70233 CAI23050 | ||||||||||||||||||
| RNA Seq Atlas | 26292 | ||||||||||||||||||