Version 5.4
Homo sapiens Protein: ZNF384
Summary
InnateDB Protein IDBP-236734.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF384
Protein Name zinc finger protein 384
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000380019
InnateDB Gene IDBG-14787 (ZNF384)
Protein Structure
UniProt Annotation
Function Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1 (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0017124 SH3 domain binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006913 nucleocytoplasmic transport
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050714 positive regulation of protein secretion
Cellular Component
GO:0005634 nucleus
GO:0005925 focal adhesion
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TF68
PhosphoSite PhosphoSite-Q8TF68
TrEMBL F5H3Z9
UniProt Splice Variant
Entrez Gene 171017
UniGene Hs.103315
RefSeq NP_001129206
HUGO HGNC:11955
OMIM 609951
CCDS CCDS44817
HPRD 18332
IMGT
EMBL AB070238 AC125494 AK095734 AK298962 BC053361 CH471116 DQ323639 U80738
GenPept AAB91437 AAH53361 ABD27870 BAB85125 BAC04618 BAG61058 EAW88755 EAW88756 EAW88757 EAW88758

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca