Version 5.4
Homo sapiens Protein: SNX6
Summary
InnateDB Protein IDBP-237300.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX6
Protein Name sorting nexin 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379779
InnateDB Gene IDBG-4564 (SNX6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 50 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 50 [view]
Protein-Protein 49 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035091 phosphatidylinositol binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006886 intracellular protein transport
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0042147 retrograde transport, endosome to Golgi
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030659 cytoplasmic vesicle membrane
GO:0031901 early endosome membrane
Protein Structure and Domains
PDB ID
InterPro IPR001683 Phox homologous domain
IPR004148 BAR domain
IPR015404 Vps5 C-terminal
PFAM PF00787
PF03114
PF09325
PRINTS
PIRSF
SMART SM00312
SM00721
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UNH7
PhosphoSite PhosphoSite-Q9UNH7
TrEMBL Q5QTQ6
UniProt Splice Variant
Entrez Gene 58533
UniGene Hs.720717
RefSeq NP_067072
HUGO HGNC:14970
OMIM 606098
CCDS CCDS9648
HPRD 12086
IMGT
EMBL AF109364 AF121856 AK021456 AL445363 AL445883 BC001798 CH471078 U83194
GenPept AAD24202 AAD27829 AAH01798 AAQ13512 BAG51034 EAW65913 EAW65915

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca