Version 5.4
Homo sapiens Protein: AFP
Summary
InnateDB Protein IDBP-23785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AFP
Protein Name alpha-fetoprotein
Synonyms AFPD; FETA; HPAFP;
Species Homo sapiens
Ensembl Protein ENSP00000226359
InnateDB Gene IDBG-23783 (AFP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000264 ALB/AFP/VDB
IPR001703 Alpha-fetoprotein
IPR014760 Serum albumin, N-terminal
IPR020858 Serum albumin-like
IPR021177 Serum albumin/Alpha-fetoprotein
PFAM PF00273
PRINTS PR00802
PR00803
PIRSF PIRSF002520
SMART SM00103
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3KMX3
UniProt Splice Variant
Entrez Gene 174
UniGene Hs.707532
RefSeq
HUGO HGNC:317
OMIM 104150
CCDS
HPRD 00074
IMGT
EMBL AC108157
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca