Version 5.4
Homo sapiens Protein: RAE1
Summary
InnateDB Protein IDBP-238723.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAE1
Protein Name RAE1 RNA export 1 homolog (S. pombe)
Synonyms dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; MRNP41;
Species Homo sapiens
Ensembl Protein ENSP00000379182
InnateDB Gene IDBG-82129 (RAE1)
Protein Structure
UniProt Annotation
Function Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:9256445}. Nucleus {ECO:0000269PubMed:9256445}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 97 experimentally validated interaction(s) in this database.
Experimentally validated
Total 97 [view]
Protein-Protein 96 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0005975 carbohydrate metabolic process
GO:0006406 mRNA export from nucleus
GO:0007077 mitotic nuclear envelope disassembly
GO:0008645 hexose transport
GO:0010827 regulation of glucose transport
GO:0015758 glucose transport
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0044281 small molecule metabolic process
GO:0055085 transmembrane transport
GO:0071407 cellular response to organic cyclic compound
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005640 nuclear outer membrane
GO:0005643 nuclear pore
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P78406
PhosphoSite PhosphoSite-P78406
TrEMBL B0QZ37
UniProt Splice Variant
Entrez Gene 8480
UniGene Hs.740197
RefSeq NP_003601
HUGO HGNC:9828
OMIM 603343
CCDS CCDS13458
HPRD 11939
IMGT
EMBL AK292247 AL109955 AL135939 AY349350 BC103754 BC106923 BC106924 CH471077 U84720 U85943
GenPept AAC28126 AAC28127 AAI03755 AAI06924 AAI06925 AAR04856 BAF84936 CAI21524 CAX15041 EAW75523 EAW75524 EAW75525

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca