Version 5.4
Homo sapiens Protein: NXF3
Summary
InnateDB Protein IDBP-240299.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NXF3
Protein Name nuclear RNA export factor 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000378504
InnateDB Gene IDBG-80369 (NXF3)
Protein Structure
UniProt Annotation
Function May function as a tissue-specific nuclear mRNA export factor.
Subcellular Localization Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Disease Associations
Tissue Specificity Expressed at high level in testis and at low level in a small number of tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
Biological Process
GO:0006406 mRNA export from nucleus
GO:0006810 transport
GO:0016973 poly(A)+ mRNA export from nucleus
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0042272 nuclear RNA export factor complex
Protein Structure and Domains
PDB ID
InterPro IPR002075 Nuclear transport factor 2
IPR015245 Nuclear RNA export factor Tap, RNA-binding domain
IPR018222 Nuclear transport factor 2, eukaryote
PFAM PF02136
PF09162
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H4D5
PhosphoSite PhosphoSite-Q9H4D5
TrEMBL
UniProt Splice Variant
Entrez Gene 56000
UniGene Hs.60386
RefSeq NP_071335
HUGO HGNC:8073
OMIM 300316
CCDS CCDS14503
HPRD 02261
IMGT
EMBL AF346619 AJ277527 AJ277660 BC031616 CH471190 Z75746
GenPept AAH31616 AAL07564 CAC16589 CAC20434 CAI41984 EAW54722

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca