Version 5.4
Homo sapiens Protein: C10orf54
Summary
InnateDB Protein IDBP-240529.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C10orf54
Protein Name chromosome 10 open reading frame 54
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000378409
InnateDB Gene IDBG-77670 (C10orf54)
Protein Structure
UniProt Annotation
Function May stimulate MMP14-mediated MMP2 activation. {ECO:0000269PubMed:20666777}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:20666777}; Single-pass type I membrane protein {ECO:0000269PubMed:20666777}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002725 negative regulation of T cell cytokine production
GO:0030509 BMP signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0048863 stem cell differentiation
GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000738 positive regulation of stem cell differentiation
Cellular Component
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H7M9
PhosphoSite PhosphoSite-Q9H7M9
TrEMBL
UniProt Splice Variant
Entrez Gene 64115
UniGene Hs.685837
RefSeq NP_071436
HUGO HGNC:30085
OMIM 615608
CCDS CCDS31218
HPRD 15160
IMGT
EMBL AF289594 AK024449 AL731541 AY265805 AY358379 BC020568 BC127257 EF506490
GenPept AAH20568 AAI27258 AAL55778 AAP03084 AAQ88745 ABP88253 BAB15739 CAI40842

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca