InnateDB Protein
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IDBP-240881.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC9B2
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Protein Name
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solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000378265
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InnateDB Gene
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IDBG-32382 (SLC9B2)
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Protein Structure
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Function |
Electroneutral exchange of protons for Na(+) and Li(+) across the inner mitochondrial membrane. Contributes to the organellar volume homeostasis. Required for osteoclast differentiation and bone resorption activity (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Detected in red blood cells (at protein level).
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0015299
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solute:proton antiporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR006153
Cation/H+ exchanger
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PFAM |
PF00999
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q86UD5
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PhosphoSite |
PhosphoSite-Q86UD5
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TrEMBL |
D6RGJ7
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UniProt Splice Variant |
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Entrez Gene |
133308
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UniGene |
Hs.706363
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RefSeq |
NP_849155
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HUGO |
HGNC:25143
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OMIM |
611789
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CCDS |
CCDS3662
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HPRD |
14051
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IMGT |
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EMBL |
AC097485
AK172823
BC009732
BC047447
CH471057
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GenPept |
AAH09732
AAH47447
BAD18790
EAX06159
EAX06161
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