Homo sapiens Gene: SLC9B2
Summary
InnateDB Gene IDBG-32382.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC9B2
Gene Name solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164038
Encoded Proteins
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Sodium hydrogen antiporters, such as NHEDC2, convert the proton motive force established by the respiratory chain or the F1F0 mitochondrial ATPase into sodium gradients that drive other energy-requiring processes, transduce environmental signals into cell responses, or function in drug efflux (Xiang et al., 2007 [PubMed 18000046]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:103019868-103085829
Strand Reverse strand
Band q24
Transcripts
ENST00000362026 ENSP00000354574
ENST00000394785 ENSP00000378265
ENST00000506288 ENSP00000421943
ENST00000503103 ENSP00000425385
ENST00000503230 ENSP00000422477
ENST00000510976
ENST00000515424
ENST00000503818 ENSP00000426305
ENST00000505838
ENST00000508136 ENSP00000423496
ENST00000512806
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015299 solute:proton antiporter activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
GO:0055114 oxidation-reduction process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Stimuli-sensing channels pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.706363
RefSeq NM_001300754 NM_001300756 NM_178833 XM_005262757 XM_006714084 XM_006714085 XM_006714086 XM_006714087
HUGO
OMIM
CCDS CCDS3662 CCDS75173 CCDS75174
HPRD 14051
IMGT
EMBL
GenPept
RNA Seq Atlas