InnateDB Protein
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IDBP-240982.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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INTS12
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Protein Name
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integrator complex subunit 12
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000378221
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InnateDB Gene
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IDBG-33032 (INTS12)
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Protein Structure
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Function |
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
12
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001965
Zinc finger, PHD-type
IPR011011
Zinc finger, FYVE/PHD-type
IPR019787
Zinc finger, PHD-finger
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PFAM |
PF00628
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PRINTS |
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PIRSF |
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SMART |
SM00249
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TIGRFAMs |
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Modification |
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SwissProt |
Q96CB8
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PhosphoSite |
PhosphoSite-Q96CB8
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TrEMBL |
E9PGI3
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UniProt Splice Variant |
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Entrez Gene |
57117
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UniGene |
Hs.480454
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RefSeq |
XP_005263205
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HUGO |
HGNC:25067
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OMIM |
611355
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CCDS |
CCDS3671
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HPRD |
11271
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IMGT |
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EMBL |
AC008243
AC093782
AC105391
AF242524
AK314939
BC014442
BK005729
CH471057
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GenPept |
AAF99604
AAH14442
BAG37445
DAA05729
EAX06189
EAX06190
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