InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PCDH1

Summary

InnateDB Protein

IDBP-241390.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PCDH1

Protein Name

protocadherin 1

Synonyms

PC42; PCDH42;

Species

Homo sapiens

Ensembl Protein

ENSP00000378043

InnateDB Gene

IDBG-50917 (PCDH1)

Protein Structure

UniProt Annotation

Function

May be involved in cell-cell interaction processes and in cell adhesion.

Subcellular Localization

Cell junction. Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries.

Disease Associations

Tissue Specificity

Highly expressed in the brain and neuro-glial cells.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding

Biological Process

GO:0007156	homophilic cell adhesion
GO:0007267	cell-cell signaling
GO:0007399	nervous system development

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0005911	cell-cell junction
GO:0016020	membrane
GO:0016021	integral component of membrane