InnateDB Protein
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IDBP-241448.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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UGT8
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Protein Name
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UDP glycosyltransferase 8
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Synonyms
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CGT; UGT4;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000378019
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InnateDB Gene
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IDBG-35210 (UGT8)
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Protein Structure
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Function |
Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0003851
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2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity
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GO:0016758
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transferase activity, transferring hexosyl groups
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GO:0030246
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carbohydrate binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002213
UDP-glucuronosyl/UDP-glucosyltransferase
IPR007235
Glycosyl transferase, family 28, C-terminal
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PFAM |
PF00201
PF04101
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q16880
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PhosphoSite |
PhosphoSite-Q16880
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TrEMBL |
D6RFW2
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UniProt Splice Variant |
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Entrez Gene |
7368
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UniGene |
Hs.743468
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RefSeq |
NP_003351
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HUGO |
HGNC:12555
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OMIM |
601291
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CCDS |
CCDS3705
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HPRD |
03186
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IMGT |
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EMBL |
AC122938
AC127386
AK127970
BC075069
CH471057
U30930
U31353
U31461
U31658
U31861
U32370
U62899
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GenPept |
AAC50565
AAC50815
AAC51187
AAH75069
BAG54609
EAX06307
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