InnateDB Protein
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IDBP-242184.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CNPY3
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Protein Name
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canopy 3 homolog (zebrafish)
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Synonyms
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CAG4A; ERDA5; PRAT4A; TNRC5;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377698
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InnateDB Gene
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IDBG-87405 (CNPY3)
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Protein Structure
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Function |
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity). {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR021852
Domain of unknown function DUF3456
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PFAM |
PF11938
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BT09
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PhosphoSite |
PhosphoSite-Q9BT09
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
10695
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UniGene |
|
RefSeq |
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HUGO |
HGNC:11968
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OMIM |
610774
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CCDS |
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HPRD |
06745
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IMGT |
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EMBL |
AF161347
AK090425
AL035587
AY358960
BC004423
BC008133
BC008898
BC008961
BC022093
U80744
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GenPept |
AAB91442
AAF28907
AAH04423
AAH08898
AAH08961
AAH22093
AAQ89319
BAC03406
CAB75301
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