InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: F9

Summary

InnateDB Protein

IDBP-242301.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Protein Name

coagulation factor IX

Synonyms

FIX; HEMB; P19; PTC; THPH8;

Species

Homo sapiens

Ensembl Protein

ENSP00000377650

InnateDB Gene

IDBG-87825 (F9)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	3 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005509	calcium ion binding

Biological Process

GO:0006508	proteolysis
GO:0007596	blood coagulation
GO:0007597	blood coagulation, intrinsic pathway
GO:0007598	blood coagulation, extrinsic pathway
GO:0017187	peptidyl-glutamic acid carboxylation
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005576	extracellular region
GO:0005788	endoplasmic reticulum lumen
GO:0005796	Golgi lumen
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR012224 Peptidase S1A, coagulation factor VII/IX/X/C/Z

PFAM

PF00594
PF00089

PRINTS

PR00001
PR00722

PIRSF

PIRSF001143

SMART

SM00069
SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References