Version 5.4
Homo sapiens Protein: FBXW7
Summary
InnateDB Protein IDBP-242551.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXW7
Protein Name F-box and WD repeat domain containing 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377528
InnateDB Gene IDBG-41233 (FBXW7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 123 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 124 [view]
Protein-Protein 123 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR001810 F-box domain
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF00646
PF12937
PF13013
PRINTS PR00320
PIRSF
SMART SM00320
SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H9CWI3
UniProt Splice Variant
Entrez Gene 55294
UniGene Hs.724181
RefSeq
HUGO HGNC:16712
OMIM 606278
CCDS
HPRD 05888
IMGT
EMBL AB333777 AC023424 AC080078 AK294568 JQ410470 JQ410471
GenPept AFD64626 AFD64627 BAF73721 BAH11814

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca