Version 5.4
Homo sapiens Protein: LOXL3
Summary
InnateDB Protein IDBP-242595.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LOXL3
Protein Name lysyl oxidase-like 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377512
InnateDB Gene IDBG-57846 (LOXL3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004720 protein-lysine 6-oxidase activity
GO:0005044 scavenger receptor activity
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
Biological Process
GO:0001837 epithelial to mesenchymal transition
GO:0006898 receptor-mediated endocytosis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001190 SRCR domain
IPR001695 Lysyl oxidase
IPR017448 SRCR-like domain
PFAM PF00530
PF01186
PRINTS PR00258
PR00074
PIRSF
SMART SM00202
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58215
PhosphoSite PhosphoSite-P58215
TrEMBL Q8N505
UniProt Splice Variant
Entrez Gene 84695
UniGene Hs.469045
RefSeq NP_001276094
HUGO HGNC:13869
OMIM 607163
CCDS CCDS74527
HPRD 06200
IMGT
EMBL AC005033 AC005041 AF282619 AF284815 AF311313 BC033130 BC071865 CH471053 DQ378059
GenPept AAH33130 AAH71865 AAK51671 AAK63205 AAK91134 ABD23013 EAW99615 EAW99616

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca