InnateDB Protein
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IDBP-242821.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ATP6V0A1
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Protein Name
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ATPase, H+ transporting, lysosomal V0 subunit a1
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Synonyms
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a1; ATP6N1; ATP6N1A; Stv1; Vph1; VPP1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377415
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InnateDB Gene
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IDBG-50881 (ATP6V0A1)
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Protein Structure
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Function |
Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Melanosome. Note=Coated vesicle. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
23
[view]
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Protein-Protein |
23
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002490
V-type ATPase, V0 complex, 116kDa subunit family
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PFAM |
PF01496
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q93050
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PhosphoSite |
PhosphoSite-Q93050
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TrEMBL |
K7EM24
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UniProt Splice Variant |
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Entrez Gene |
535
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UniGene |
Hs.463074
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RefSeq |
NP_005168
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HUGO |
HGNC:865
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OMIM |
192130
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CCDS |
CCDS11426
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HPRD |
01886
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IMGT |
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EMBL |
AC067852
AC107993
AK295682
AK316305
AL137683
BC032398
CH471152
Z71460
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GenPept |
AAH32398
BAH12153
BAH14676
CAA96077
CAB70874
EAW60830
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