InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ART1

Summary

InnateDB Protein

IDBP-24343.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ART1

Protein Name

ADP-ribosyltransferase 1

Synonyms

ART2; ARTC1; CD296; RT6;

Species

Homo sapiens

Ensembl Protein

ENSP00000250693

InnateDB Gene

IDBG-24341 (ART1)

Protein Structure

UniProt Annotation

Function

Has ADP-ribosyltransferase activity toward GLP1R. {ECO:0000269PubMed:21901419}.

Subcellular Localization

Sarcoplasmic reticulum membrane; Lipid- anchor, GPI-anchor.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003950	NAD+ ADP-ribosyltransferase activity
GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity

Biological Process

GO:0006471	protein ADP-ribosylation
GO:0045087	innate immune response

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009986	cell surface
GO:0031225	anchored component of membrane
GO:0033017	sarcoplasmic reticulum membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000768 NAD:arginine ADP-ribosyltransferase, ART

PFAM

PF01129

PRINTS

PR00970

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P52961

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

417

UniGene

Hs.382188

RefSeq

NP_004305

HUGO

HGNC:723

OMIM

601625

CCDS

CCDS7744

HPRD

03377

IMGT

EMBL

AJ291430 BC069102 BC111729 CH471158 S74683

GenPept

AAB32387 AAH69102 AAI11730 CAC69964 EAX02559