InnateDB Protein
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IDBP-243530.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TES
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Protein Name
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testis derived transcript (3 LIM domains)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377121
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InnateDB Gene
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IDBG-37196 (TES)
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Protein Structure
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Function |
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth. {ECO:0000269PubMed:11420696, ECO:0000269PubMed:12571287, ECO:0000269PubMed:12695497}.
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Subcellular Localization |
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. {ECO:0000269PubMed:11420696}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
33
[view]
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Protein-Protein |
31
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001781
Zinc finger, LIM-type
IPR010442
PET domain
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PFAM |
PF00412
PF06297
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PRINTS |
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PIRSF |
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SMART |
SM00132
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UGI8
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PhosphoSite |
PhosphoSite-Q9UGI8
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TrEMBL |
Q9Y423
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UniProt Splice Variant |
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Entrez Gene |
26136
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UniGene |
Hs.630572
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RefSeq |
NP_690042
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HUGO |
HGNC:14620
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OMIM |
606085
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CCDS |
CCDS5764
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HPRD |
05833
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IMGT |
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EMBL |
AC073130
AF245356
AF245357
AF260225
AJ250865
AK021575
AK291802
AK300546
AL050162
BC001451
CH236947
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GenPept |
AAG17612
AAG17613
AAG17635
AAG17636
AAH01451
AAQ93367
BAB13846
BAF84491
BAH13301
CAB43302
CAB65119
EAL24365
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