Homo sapiens Protein: PRCP
Summary
InnateDB Protein IDBP-243688.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRCP
Protein Name prolylcarboxypeptidase (angiotensinase C)
Synonyms HUMPCP; PCP;
Species Homo sapiens
Ensembl Protein ENSP00000377055
InnateDB Gene IDBG-66177 (PRCP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 12 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0004185 serine-type carboxypeptidase activity
GO:0005515 protein binding
GO:0008236 serine-type peptidase activity
Biological Process
GO:0002155 regulation of thyroid hormone mediated signaling pathway
GO:0002353 plasma kallikrein-kinin cascade
GO:0003085 negative regulation of systemic arterial blood pressure
GO:0006508 proteolysis
GO:0007596 blood coagulation
GO:0007597 blood coagulation, intrinsic pathway
GO:0042593 glucose homeostasis
GO:0043535 regulation of blood vessel endothelial cell migration
GO:0060055 angiogenesis involved in wound healing
GO:0097009 energy homeostasis
GO:2000377 regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005764 lysosome
GO:0005886 plasma membrane
GO:0045178 basal part of cell
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008758 Peptidase S28
IPR029058 Alpha/Beta hydrolase fold
PFAM PF05577
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P42785
PhosphoSite PhosphoSite-P42785
TrEMBL E9PR42
UniProt Splice Variant
Entrez Gene 5547
UniGene Hs.706856
RefSeq NP_955450
HUGO HGNC:9344
OMIM 176785
CCDS CCDS41695
HPRD 08352
IMGT
EMBL AB451270 AB451397 AK090847 AK091786 AK302386 AK312919 AP000893 AP001646 BC001500 CH471076 L13977
GenPept AAA99891 AAH01500 BAG35764 BAG52238 BAG52417 BAG70084 BAG70211 BAH13692 EAW75074 EAW75075