InnateDB Protein
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IDBP-243823.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MGAT1
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Protein Name
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mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
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Synonyms
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GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; MGAT;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377010
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InnateDB Gene
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IDBG-62498 (MGAT1)
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Protein Structure
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Function |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
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Subcellular Localization |
Golgi apparatus membrane; Single-pass type II membrane protein.
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Disease Associations |
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Tissue Specificity |
Appears to be present in all tissues.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003827
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alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
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GO:0008375
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acetylglucosaminyltransferase activity
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GO:0046872
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metal ion binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004139
Glycosyl transferase, family 13
IPR029044
Nucleotide-diphospho-sugar transferases
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PFAM |
PF03071
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P26572
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PhosphoSite |
PhosphoSite-P26572
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TrEMBL |
Q59G70
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UniProt Splice Variant |
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Entrez Gene |
4245
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UniGene |
Hs.519818
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RefSeq |
NP_001108089
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HUGO |
HGNC:7044
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OMIM |
160995
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CCDS |
CCDS4458
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HPRD |
01189
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IMGT |
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EMBL |
AB209239
AC022413
AK092256
AK094130
AK290769
BC003575
CH471165
CR456861
M55621
M61829
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GenPept |
AAA52563
AAA75523
AAH03575
BAD92476
BAF83458
BAG52510
BAG52821
CAG33142
EAW53739
EAW53740
EAW53741
EAW53742
EAW53743
EAW53744
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