Version 5.4
Homo sapiens Protein: TSPAN8
Summary
InnateDB Protein IDBP-243841.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN8
Protein Name tetraspanin 8
Synonyms CO-029; TM4SF3;
Species Homo sapiens
Ensembl Protein ENSP00000377003
InnateDB Gene IDBG-47950 (TSPAN8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Gastric, colon, rectal, and pancreatic carcinomas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
Biological Process
GO:0006486 protein glycosylation
GO:0007165 signal transduction
GO:0030195 negative regulation of blood coagulation
Cellular Component
GO:0005764 lysosome
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000301 Tetraspanin
IPR008952 Tetraspanin, EC2 domain
IPR018499 Tetraspanin/Peripherin
PFAM PF00335
PRINTS PR00259
PIRSF PIRSF002419
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P19075
PhosphoSite PhosphoSite-P19075
TrEMBL
UniProt Splice Variant
Entrez Gene 7103
UniGene Hs.170563
RefSeq
HUGO HGNC:11855
OMIM 600769
CCDS CCDS8999
HPRD 02865
IMGT
EMBL AK313112 BC005246 CH471054 M35252
GenPept AAA35709 AAH05246 BAG35934 EAW97257

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca