Version 5.4
Homo sapiens Protein: OSGIN1
Summary
InnateDB Protein IDBP-243900.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSGIN1
Protein Name oxidative stress induced growth inhibitor 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000376983
InnateDB Gene IDBG-43985 (OSGIN1)
Protein Structure
UniProt Annotation
Function Regulates the differentiation and proliferation of normal cells through the regulation of cell death. {ECO:0000269PubMed:11459809, ECO:0000269PubMed:14570898}.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous. Highest expression in the ovary, testis, kidney, and liver. {ECO:0000269PubMed:11459809, ECO:0000269PubMed:14570898}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0007275 multicellular organismal development
GO:0030154 cell differentiation
GO:0030308 negative regulation of cell growth
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID
InterPro IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain
PFAM PF07992
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UJX0
PhosphoSite PhosphoSite-Q9UJX0
TrEMBL J3KRK7
UniProt Splice Variant
Entrez Gene 29948
UniGene Hs.128055
RefSeq NP_892026
HUGO HGNC:30093
OMIM 607975
CCDS CCDS10939
HPRD 06412
IMGT
EMBL AC040169 AF191740 AF334780 AK290383 AY037158 AY258066 AY258067 AY258068 BC032476 BC093687 BC113417 CH471114
GenPept AAF06662 AAH32476 AAH93687 AAI13418 AAK01722 AAK67637 AAP14662 AAP14663 AAP14664 BAF83072 EAW95511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca