InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GRM5

Summary

InnateDB Protein

IDBP-243910.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GRM5

Protein Name

glutamate receptor, metabotropic 5

Synonyms

GPRC1E; mGlu5; MGLUR5; PPP1R86;

Species

Homo sapiens

Ensembl Protein

ENSP00000376972

InnateDB Gene

IDBG-67198 (GRM5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007186

G-protein coupled receptor signaling pathway

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000202 GPCR, family 3, metabotropic glutamate receptor 5
IPR000337 GPCR, family 3
IPR001828 Extracellular ligand-binding receptor
IPR028082 Periplasmic binding protein-like I

PFAM

PF01094

PRINTS

PR01055
PR00248

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite