Homo sapiens Protein: CD3D
Summary
InnateDB Protein IDBP-244747.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD3D
Protein Name CD3d molecule, delta (CD3-TCR complex)
Synonyms CD3-DELTA; IMD19; T3D;
Species Homo sapiens
Ensembl Protein ENSP00000376622
InnateDB Gene IDBG-73628 (CD3D)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004888 transmembrane signaling receptor activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0030217 T cell differentiation
GO:0031295 T cell costimulation
GO:0045059 positive thymic T cell selection
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050776 regulation of immune response
GO:0050852 T cell receptor signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042101 T cell receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR003110 Phosphorylated immunoreceptor signalling ITAM
PFAM PF02189
PRINTS
PIRSF
SMART SM00077
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P04234
PhosphoSite PhosphoSite-P04234
TrEMBL G8H453
UniProt Splice Variant
Entrez Gene 915
UniGene
RefSeq NP_001035741
HUGO HGNC:1673
OMIM 186790
CCDS CCDS41724
HPRD 01730
IMGT
EMBL AP001582 BC039035 BC070321 CD014058 JN392070 M12726 M12727 X01451 X03934
GenPept AAA51792 AAH39035 AAH70321 AEQ93557 CAA25683 CAA27573