Version 5.4
Homo sapiens Protein: KCNJ1
Summary
InnateDB Protein IDBP-245197.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNJ1
Protein Name potassium inwardly-rectifying channel, subfamily J, member 1
Synonyms KIR1.1; ROMK; ROMK1;
Species Homo sapiens
Ensembl Protein ENSP00000376433
InnateDB Gene IDBG-75955 (KCNJ1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
GO:0005524 ATP binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0007588 excretion
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003268 Potassium channel, inwardly rectifying, Kir1.1
IPR014756 Immunoglobulin E-set
IPR016449 Potassium channel, inwardly rectifying, Kir
PFAM PF01007
PRINTS PR01321
PR01320
PIRSF PIRSF005465
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48048
PhosphoSite PhosphoSite-P48048
TrEMBL A0A024R3K6
UniProt Splice Variant
Entrez Gene 3758
UniGene Hs.527830
RefSeq
HUGO HGNC:6255
OMIM 600359
CCDS CCDS8477
HPRD 08981
IMGT
EMBL BC074752 BC136360 BC136361 CH471065 S78737 U03884 U12541 U12542 U12543 U12544 U12545 U65406
GenPept AAA20594 AAA61712 AAA61713 AAA61714 AAA61715 AAA61716 AAB35012 AAC51220 AAC51221 AAC51222 AAH74752 AAI36361 AAI36362 EAW67721 EAW67722 EAW67723 EAW67724

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca