Homo sapiens Protein: PPFIBP1
Summary
InnateDB Protein IDBP-24583.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPFIBP1
Protein Name PTPRF interacting protein, binding protein 1 (liprin beta 1)
Synonyms hSGT2; hSgt2p; L2; SGT2;
Species Homo sapiens
Ensembl Protein ENSP00000228425
InnateDB Gene IDBG-24579 (PPFIBP1)
Protein Structure
UniProt Annotation
Function May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. {ECO:0000269PubMed:9624153}.
Subcellular Localization
Disease Associations
Tissue Specificity Widely expressed. Absent in liver. {ECO:0000269PubMed:9624153}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 20 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR001660 Sterile alpha motif domain
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1
PFAM PF07647
PF00536
PRINTS
PIRSF
SMART SM00454
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86W92
PhosphoSite PhosphoSite-Q86W92
TrEMBL F5H6Q7
UniProt Splice Variant
Entrez Gene 8496
UniGene Hs.172445
RefSeq NP_003613
HUGO HGNC:9249
OMIM 603141
CCDS CCDS8713
HPRD 04390
IMGT
EMBL AB033056 AB049149 AC009509 AC068794 AC087257 AF034802 AJ276680 BC046159 BC050281
GenPept AAC26103 AAH46159 AAH50281 BAA86544 BAB39690 CAB77544