InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BOLL

Summary

InnateDB Protein

IDBP-245943.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BOLL

Protein Name

bol, boule-like (Drosophila)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000376116

InnateDB Gene

IDBG-78064 (BOLL)

Protein Structure

UniProt Annotation

Function

Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:11390979, ECO:0000269PubMed:17114206}.

Disease Associations

Tissue Specificity

Testis specific. Not expressed in early embryos, primordial germ cells and spermatogonial cells. First expressed in the cytoplasm of spermatocytes and then persists through meiosis. {ECO:0000269PubMed:11390979, ECO:0000269PubMed:17114206}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0008494	translation activator activity

Biological Process

GO:0007126	meiotic nuclear division
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0030154	cell differentiation
GO:0045948	positive regulation of translational initiation