InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SUMO1

Summary

InnateDB Protein

IDBP-246054.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SUMO1

Protein Name

SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)

Synonyms

DAP1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C; SMT3H3; UBL1;

Species

Homo sapiens

Ensembl Protein

ENSP00000376075

InnateDB Gene

IDBG-78849 (SUMO1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1363 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Experimentally validated
Total	1363 [view]
Protein-Protein	1353 [view]
Protein-DNA	6 [view]
Protein-RNA	0
DNA-DNA	4 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006281	DNA repair
GO:0016925	protein sumoylation
GO:0019221	cytokine-mediated signaling pathway
GO:0031334	positive regulation of protein complex assembly
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032880	regulation of protein localization
GO:0043392	negative regulation of DNA binding
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0045892	negative regulation of transcription, DNA-templated
GO:0060021	palate development
GO:0060333	interferon-gamma-mediated signaling pathway
GO:0060334	regulation of interferon-gamma-mediated signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005643	nuclear pore
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0016605	PML body
GO:0016607	nuclear speck
GO:0031965	nuclear membrane