InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SP140

Summary

InnateDB Protein

IDBP-246459.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SP140

Protein Name

SP140 nuclear body protein

Synonyms

LYSP100; LYSP100-A; LYSP100-B;

Species

Homo sapiens

Ensembl Protein

ENSP00000375899

InnateDB Gene

IDBG-82911 (SP140)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006952	defense response

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005654	nucleoplasm
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000770 SAND domain
IPR001487 Bromodomain
IPR001965 Zinc finger, PHD-type
IPR004865 Sp100
IPR010919 SAND domain-like
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM

PF01342
PF00439
PF03172
PF00628

PRINTS

PR00503

PIRSF

SMART

SM00258
SM00297
SM00249

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt