InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPP5C

Summary

InnateDB Protein

IDBP-246716.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP5C

Protein Name

protein phosphatase 5, catalytic subunit

Synonyms

PP5; PPP5; PPT;

Species

Homo sapiens

Ensembl Protein

ENSP00000375786

InnateDB Gene

IDBG-58687 (PPP5C)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 77 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	77 [view]
Protein-Protein	72 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0005515	protein binding
GO:0016787	hydrolase activity

Biological Process

GO:0006470

protein dephosphorylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

InterPro

IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR013026 Tetratricopeptide repeat-containing domain
IPR013235 PPP domain
IPR029052 Metallo-dependent phosphatase-like

PFAM

PF00149
PF08321

PRINTS

PR00114

PIRSF

SMART

SM00156

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt