InnateDB Protein
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IDBP-24675.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SREK1
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Protein Name
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splicing regulatory glutamine/lysine-rich protein 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000334538
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InnateDB Gene
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IDBG-24671 (SREK1)
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Protein Structure
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Function |
Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 73 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
73
[view]
|
Protein-Protein |
73
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000504
RNA recognition motif domain
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PFAM |
PF00076
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PRINTS |
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PIRSF |
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q8WXA9
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PhosphoSite |
PhosphoSite-Q8WXA9
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TrEMBL |
Q69YM5
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UniProt Splice Variant |
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Entrez Gene |
140890
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UniGene |
Hs.717970
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RefSeq |
NP_001070667
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HUGO |
HGNC:17882
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OMIM |
609268
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CCDS |
CCDS43323
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HPRD |
18043
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IMGT |
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EMBL |
AC008772
AC025442
AF459094
AL832888
BC047322
BC067770
BC112343
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GenPept |
AAH47322
AAH67770
AAI12344
AAL67778
CAH10414
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