InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cdh2

Summary

InnateDB Protein

IDBP-248733.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Cdh2

Protein Name

cadherin 2

Synonyms

CDHN; N-cadherin; Ncad;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000111516

InnateDB Gene

IDBG-129545 (Cdh2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.

Experimentally validated
Total	40 [view]
Protein-Protein	38 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	57 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion
GO:0007157	heterophilic cell-cell adhesion
GO:0016339	calcium-dependent cell-cell adhesion
GO:0016477	cell migration
GO:0043410	positive regulation of MAPK cascade
GO:0048514	blood vessel morphogenesis
GO:0051146	striated muscle cell differentiation
GO:0090090	negative regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005911	cell-cell junction
GO:0005912	adherens junction
GO:0005916	fascia adherens
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0030027	lamellipodium
GO:0045202	synapse