InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trmt2a

Summary

InnateDB Protein

IDBP-249185.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Trmt2a

Protein Name

TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)

Synonyms

Htf9c;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000111304

InnateDB Gene

IDBG-141275 (Trmt2a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0008168	methyltransferase activity
GO:0008173	RNA methyltransferase activity
GO:0008176	tRNA (guanine-N7-)-methyltransferase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001510	RNA methylation
GO:0006396	RNA processing
GO:0006400	tRNA modification
GO:0006464	cellular protein modification process
GO:0008152	metabolic process

Cellular Component

Protein Structure and Domains

PDB ID

MGI:96270

InterPro

IPR000241 Putative RNA methylase domain
IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase
IPR003358 tRNA (guanine-N-7) methyltransferase
IPR007848 Methyltransferase small domain
IPR010280 (Uracil-5)-methyltransferase family
IPR013216 Methyltransferase type 11
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01170
PF01135
PF02390
PF05175
PF05958
PF08241

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-