Version 5.4
Mus musculus Gene: Trmt2a
Summary
InnateDB Gene IDBG-141275.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trmt2a
Gene Name TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
Synonyms Htf9c
Species Mus musculus
Ensembl Gene ENSMUSG00000022721
Encoded Proteins
IDBP-249186
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
IDBP-249185
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
IDBP-532372
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
IDBP-538738
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
IDBP-625662
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099899:
The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:18248679-18254772
Strand Forward strand
Band A3
Transcripts
ENSMUST00000059696
ENSMUST00000100099 ENSMUSP00000111303
ENSMUST00000115640 ENSMUSP00000111304
ENSMUST00000127239
ENSMUST00000140206 ENSMUSP00000121216
ENSMUST00000153292
ENSMUST00000147273
ENSMUST00000145112 ENSMUSP00000117026
ENSMUST00000128045 ENSMUSP00000133226
ENSMUST00000131211
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0008176 tRNA (guanine-N7-)-methyltransferase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001510 RNA methylation
GO:0006396 RNA processing
GO:0006400 tRNA modification
GO:0006464 cellular protein modification process
GO:0008152 metabolic process
GO:0031167 rRNA methylation
GO:0032259 methylation
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000099899
View Gene Order
ENSBTAG00000019871
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.271798 Mm.413813
RefSeq NM_001080999 NM_001081000 NM_001195205
OMIM
CCDS CCDS37281 CCDS37282 CCDS57020
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca