InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Suv39h1

Summary

InnateDB Protein

IDBP-249202.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Suv39h1

Protein Name

suppressor of variegation 3-9 homolog 1 (Drosophila)

Synonyms

AI852103; AL022883; DXHXS7466e; H3-K9-HMTase 1; KMT1A; mIS6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000111300

InnateDB Gene

IDBG-130058 (Suv39h1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 53 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	53 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0008276	protein methyltransferase activity
GO:0018024	histone-lysine N-methyltransferase activity

Biological Process

GO:0006323	DNA packaging
GO:0034968	histone lysine methylation
GO:0051567	histone H3-K9 methylation

Cellular Component

GO:0005634	nucleus
GO:0005720	nuclear heterochromatin

Protein Structure and Domains

PDB ID

MGI:1099440

InterPro

IPR000953 Chromo domain/shadow
IPR001214 SET domain
IPR003606 Pre-SET zinc-binding sub-group
IPR003616 Post-SET domain
IPR007728 Pre-SET domain
IPR011381 Histone H3-K9 methyltransferase
IPR016197 Chromo domain-like
IPR023780 Chromo domain

PFAM

PF00856
PF05033
PF00385

PRINTS

PIRSF

PIRSF009343

SMART

SM00298
SM00317
SM00468
SM00508

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt