Version 5.4
Mus musculus Protein: Otc
Summary
InnateDB Protein IDBP-249431.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Otc
Protein Name ornithine transcarbamylase
Synonyms AI265390; Sf; spf;
Species Mus musculus
Ensembl Protein ENSMUSP00000111190
InnateDB Gene IDBG-131648 (Otc)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016597 amino acid binding
GO:0016743 carboxyl- or carbamoyltransferase activity
Biological Process
GO:0006520 cellular amino acid metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Protein Structure and Domains
PDB ID MGI:97448
InterPro IPR002082 Aspartate carbamoyltransferase
IPR002292 Ornithine/putrescine carbamoyltransferase
IPR006130 Aspartate/ornithine carbamoyltransferase
IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain
IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding
PFAM PF00185
PF02729
PRINTS PR00101
PR00102
PR00100
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8R1A8
UniProt Splice Variant
Entrez Gene 18416
UniGene Mm.2611
RefSeq
MGI ID
MGI Symbol Otc
OMIM
CCDS
HPRD
IMGT
EMBL AL671042 BC024893
GenPept AAH24893

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca