InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Carm1

Summary

InnateDB Protein

IDBP-249737.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Carm1

Protein Name

coactivator-associated arginine methyltransferase 1

Synonyms

Prmt4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000111052

InnateDB Gene

IDBG-140748 (Carm1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	50 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008168	methyltransferase activity
GO:0008276	protein methyltransferase activity

Biological Process

GO:0003420	regulation of growth plate cartilage chondrocyte proliferation
GO:0006355	regulation of transcription, DNA-templated
GO:0006479	protein methylation
GO:0008152	metabolic process
GO:0008284	positive regulation of cell proliferation
GO:0009405	pathogenesis
GO:0016571	histone methylation
GO:0030520	intracellular estrogen receptor signaling pathway
GO:0032091	negative regulation of protein binding
GO:0060350	endochondral bone morphogenesis

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:1913208

InterPro

IPR007848 Methyltransferase small domain
IPR010456 Ribosomal L11 methyltransferase, PrmA
IPR013216 Methyltransferase type 11
IPR020989 Histone-arginine methyltransferase CARM1, N-terminal
IPR025799 Protein arginine N-methyltransferase
IPR027555 tRNA (mo5U34)-methyltransferase-like
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF05175
PF06325
PF08241
PF11531
PF05185
PF08003

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-