InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: St6gal1

Summary

InnateDB Protein

IDBP-249858.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

St6gal1

Protein Name

beta galactoside alpha 2,6 sialyltransferase 1

Synonyms

AW742324; Siat1; St6gal; St6Gal-I; St6galI;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110992

InnateDB Gene

IDBG-149606 (St6gal1)

Protein Structure

UniProt Annotation

Function

Transfers sialic acid from CMP-sialic acid to galactose- containing acceptor substrates.

Subcellular Localization

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity
GO:0008373	sialyltransferase activity

Biological Process

GO:0006054	N-acetylneuraminate metabolic process
GO:0006486	protein glycosylation
GO:0018279	protein N-linked glycosylation via asparagine
GO:0097503	sialylation