Version 5.4
Mus musculus Protein: Pot1a
Summary
InnateDB Protein IDBP-249875.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Pot1a
Protein Name protection of telomeres 1A
Synonyms 1500031H18Rik; AI851169; Pot1;
Species Mus musculus
Ensembl Protein ENSMUSP00000110982
InnateDB Gene IDBG-130394 (Pot1a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 178 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 178 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0042162 telomeric DNA binding
GO:0043047 single-stranded telomeric DNA binding
Biological Process
GO:0000723 telomere maintenance
GO:0051276 chromosome organization
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0000783 nuclear telomere cap complex
GO:0000784 nuclear chromosome, telomeric region
Protein Structure and Domains
PDB ID MGI:2141503
InterPro IPR011564 Telomeric single stranded DNA binding POT1/Cdc13
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF02765
PRINTS
PIRSF
SMART SM00976
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3UXR7
UniProt Splice Variant
Entrez Gene 101185
UniGene Mm.397208
RefSeq
MGI ID
MGI Symbol Pot1a
OMIM
CCDS
HPRD
IMGT
EMBL AC153888 AC158683 AK135346
GenPept BAE22496

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca