Mus musculus Protein: Grm8
Summary
InnateDB Protein IDBP-249891.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Grm8
Protein Name glutamate receptor, metabotropic 8
Synonyms A230002O04; Gprc1h; mGluR8;
Species Mus musculus
Ensembl Protein ENSMUSP00000110979
InnateDB Gene IDBG-130430 (Grm8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001642 group III metabotropic glutamate receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0030818 negative regulation of cAMP biosynthetic process
GO:0051966 regulation of synaptic transmission, glutamatergic
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0042734 presynaptic membrane
Protein Structure and Domains
PDB ID MGI:1351345
InterPro IPR000144 GPCR, family 3, metabotropic glutamate receptor 8
IPR000162 GPCR, family 3, metabotropic glutamate receptor
IPR000337 GPCR, family 3
IPR001786 GPCR, family 3, metabotropic glutamate receptor 4
IPR001828 Extracellular ligand-binding receptor
IPR011500 GPCR, family 3, nine cysteines domain
IPR017978 GPCR, family 3, C-terminal
IPR028082 Periplasmic binding protein-like I
PFAM PF01094
PF07562
PF00003
PRINTS PR01058
PR00593
PR00248
PR01054
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3UYA3
UniProt Splice Variant
Entrez Gene 14823
UniGene Mm.320732
RefSeq
MGI ID
MGI Symbol Grm8
OMIM
CCDS CCDS39443
HPRD
IMGT
EMBL AC035247 AC067970 AC068066 AC074223 AC079957 AC115890 AC121497 AK134845 BC051384 BC144753
GenPept AAH51384 AAI44754 BAE22309