Mus musculus Protein: Mll5
Summary
InnateDB Protein IDBP-250302.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mll5
Protein Name myeloid/lymphoid or mixed-lineage leukemia 5
Synonyms 1810033J14Rik; 9530077A04Rik; D230038D11Rik; Mll5; NKp44L;
Species Mus musculus
Ensembl Protein ENSMUSP00000110781
InnateDB Gene IDBG-139425 (Mll5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0042800 histone methyltransferase activity (H3-K4 specific)
Biological Process
GO:0002446 neutrophil mediated immunity
GO:0006306 DNA methylation
GO:0006351 transcription, DNA-templated
GO:0007050 cell cycle arrest
GO:0030218 erythrocyte differentiation
GO:0030854 positive regulation of granulocyte differentiation
GO:0042119 neutrophil activation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048384 retinoic acid receptor signaling pathway
GO:0051568 histone H3-K4 methylation
GO:0071300 cellular response to retinoic acid
Cellular Component
GO:0016607 nuclear speck
GO:0070688 MLL5-L complex
Protein Structure and Domains
PDB ID MGI:1924825
InterPro IPR001214 SET domain
IPR001965 Zinc finger, PHD-type
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger
PFAM PF00856
PF00628
PRINTS
PIRSF
SMART SM00317
SM00249
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UG20
PhosphoSite PhosphoSite-Q3UG20
TrEMBL
UniProt Splice Variant
Entrez Gene 69188
UniGene Mm.205190
RefSeq XP_006535868
MGI ID
MGI Symbol Kmt2e
OMIM
CCDS CCDS51430
HPRD
IMGT
EMBL AC122022 AK007682 AK021284 AK035078 AK148169 AK160519 BC036286 BC064079 BC089356 BC103801
GenPept AAH36286 AAH64079 AAH89356 AAI03802 BAB25186 BAC28936 BAE28389 BAE35839 BAE43262