InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cnot4

Summary

InnateDB Protein

IDBP-250625.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cnot4

Protein Name

CCR4-NOT transcription complex, subunit 4

Synonyms

Not4; Not4h; Not4hp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110645

InnateDB Gene

IDBG-135345 (Cnot4)

Protein Structure

UniProt Annotation

Function

Has E3 ubiquitin ligase activity. Involved in activation of the JAK/STAT pathway (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0045087	innate immune response (InnateDB)
GO:0051865	protein autoubiquitination