InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zc3hav1

Summary

InnateDB Protein

IDBP-250801.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Zc3hav1

Protein Name

zinc finger CCCH type, antiviral 1

Synonyms

1200014N16Rik; 2900058M19Rik; 9130009D18Rik; 9830115L13Rik; ARTD13; D6Bwg1452e; ZAP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110550

InnateDB Gene

IDBG-137011 (Zc3hav1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003950	NAD+ ADP-ribosyltransferase activity
GO:0017151	DEAD/H-box RNA helicase binding
GO:0046872	metal ion binding

Biological Process

GO:0008152	metabolic process
GO:0032481	positive regulation of type I interferon production
GO:0032781	positive regulation of ATPase activity
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087	innate immune response (InnateDB)
GO:0071360	cellular response to exogenous dsRNA

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:1926031

InterPro

IPR004170 WWE domain
IPR012317 Poly(ADP-ribose) polymerase, catalytic domain

PFAM

PF02825
PF00644

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z5I1

UniProt Splice Variant

Entrez Gene

78781

UniGene

Mm.487761

RefSeq

NP_082697

MGI ID

MGI Symbol

Zc3hav1

OMIM

CCDS

HPRD

IMGT

EMBL

AC125530

GenPept