InnateDB Protein
|
IDBP-250965.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Iqcb1
|
Protein Name
|
IQ calmodulin-binding motif containing 1
|
Synonyms
|
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000110467
|
InnateDB Gene
|
IDBG-158489 (Iqcb1)
|
Protein Structure
|
|
Function |
Involved in ciliogenesis. {ECO:0000269PubMed:21565611}.
|
Subcellular Localization |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Localization to the centrosome depends on the interaction with CEP290. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
Localized to the outer segment and connecting cilia of photoreceptor cells. {ECO:0000269PubMed:15723066}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 165 experimentally validated interaction(s) in this database.
They are also associated with 166 interaction(s) predicted by orthology.
Experimentally validated |
Total |
165
[view]
|
Protein-Protein |
165
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
166 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:2443764
|
InterPro |
IPR000048
IQ motif, EF-hand binding site
IPR016024
Armadillo-type fold
IPR027417
P-loop containing nucleoside triphosphate hydrolase
|
PFAM |
PF00612
|
PRINTS |
|
PIRSF |
|
SMART |
SM00015
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8BP00
|
PhosphoSite |
PhosphoSite-Q8BP00
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
320299
|
UniGene |
Mm.448362
|
RefSeq |
|
MGI ID |
|
MGI Symbol |
Iqcb1
|
OMIM |
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
AK078554
AK165220
BC029084
|
GenPept |
AAH29084
BAC37333
BAE38084
|
|
|