Version 5.4
Mus musculus Protein: Fstl1
Summary
InnateDB Protein IDBP-251082.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fstl1
Protein Name follistatin-like 1
Synonyms AI316791; AW107808; Fstl; TSC-36;
Species Mus musculus
Ensembl Protein ENSMUSP00000110411
InnateDB Gene IDBG-159696 (Fstl1)
Protein Structure
UniProt Annotation
Function May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008201 heparin binding
Biological Process
GO:0042594 response to starvation
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:102793
InterPro IPR002048 EF-hand domain
IPR002350 Kazal domain
IPR003645 Follistatin-like, N-terminal
IPR015369 Follistatin/Osteonectin EGF domain
PFAM PF00036
PF13202
PF13405
PF00050
PF07648
PF09289
PRINTS
PIRSF
SMART SM00054
SM00280
SM00274
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q62356
PhosphoSite PhosphoSite-Q62356
TrEMBL
UniProt Splice Variant
Entrez Gene 14314
UniGene Mm.471956
RefSeq NP_032073
MGI ID
MGI Symbol Fstl1
OMIM
CCDS CCDS37339
HPRD
IMGT
EMBL AK049440 AK147117 BC006185 BC028921 CH466521 M91380
GenPept AAC37633 AAH28921 BAC33751 BAE27689 EDK97964

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca