InnateDB Protein
|
IDBP-251147.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Dpysl5
|
Protein Name
|
dihydropyrimidinase-like 5
|
Synonyms
|
CRAM; CRMP-5; Crmp5;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000110377
|
InnateDB Gene
|
IDBG-146093 (Dpysl5)
|
Protein Structure
|
|
Function |
May have a function in neuronal differentiation and/or axon growth.
|
Subcellular Localization |
Cytoplasm {ECO:0000250}. Note=Translocates into the mitochondria upon interaction with SEPT4 isoform 4. {ECO:0000269PubMed:12581152}.
|
Disease Associations |
|
Tissue Specificity |
Detected in brain. {ECO:0000269PubMed:10956643}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
10
[view]
|
Protein-Protein |
10
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
6 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0005515
|
protein binding
|
GO:0016787
|
hydrolase activity
|
GO:0016810
|
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
|
GO:0016812
|
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:1929772
|
InterPro |
IPR006680
Amidohydrolase 1
IPR011059
Metal-dependent hydrolase, composite domain
IPR011778
Hydantoinase/dihydropyrimidinase
|
PFAM |
PF01979
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9EQF6
|
PhosphoSite |
PhosphoSite-Q9EQF6
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
65254
|
UniGene |
Mm.404495
|
RefSeq |
XP_006504108
|
MGI ID |
|
MGI Symbol |
Dpysl5
|
OMIM |
|
CCDS |
CCDS39047
|
HPRD |
|
IMGT |
|
EMBL |
AF249295
BC065054
|
GenPept |
AAG37998
AAH65054
|
|
|