Version 5.4
Mus musculus Gene: Dpysl5
Summary
InnateDB Gene IDBG-146093.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dpysl5
Gene Name dihydropyrimidinase-like 5
Synonyms CRAM; CRMP-5; Crmp5
Species Mus musculus
Ensembl Gene ENSMUSG00000029168
Encoded Proteins
IDBP-146095
dihydropyrimidinase-like 5
IDBP-146097
dihydropyrimidinase-like 5
IDBP-251147
dihydropyrimidinase-like 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157851:
This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:30711564-30799375
Strand Forward strand
Band B1
Transcripts
ENSMUST00000088081 ENSMUSP00000085400
ENSMUST00000101442 ENSMUSP00000098985
ENSMUST00000114729 ENSMUSP00000110377
ENSMUST00000127365
ENSMUST00000136657
ENSMUST00000138625
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Biological Process
GO:0006208 pyrimidine nucleobase catabolic process
GO:0007411 axon guidance
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0030425 dendrite
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000157851
View Gene Order
ENSBTAG00000018576
Not yet available
Pathways
NETPATH
REACTOME
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
REACT_263034
Semaphorin interactions pathway
REACT_244852
CRMPs in Sema3A signaling pathway
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19199
CRMPs in Sema3A signaling pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_18266
Axon guidance pathway
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27732 Mm.404495
RefSeq NM_023047 XM_006504045
OMIM
CCDS CCDS39047
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca