Version 5.4
Mus musculus Protein: Atraid
Summary
InnateDB Protein IDBP-251311.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atraid
Protein Name RIKEN cDNA 0610007C21 gene
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000110308
InnateDB Gene IDBG-147066 (Atraid)
Protein Structure
UniProt Annotation
Function Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus envelope {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Colocalizes with NELL1 on the nuclear envelope and the perinuclear region. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0010468 regulation of gene expression
GO:0030154 cell differentiation
GO:0030501 positive regulation of bone mineralization
GO:0033689 negative regulation of osteoblast proliferation
GO:0045669 positive regulation of osteoblast differentiation
GO:2000599 negative regulation of cyclin catabolic process
Cellular Component
GO:0005635 nuclear envelope
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1918918
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PGD0
PhosphoSite PhosphoSite-Q6PGD0
TrEMBL
UniProt Splice Variant
Entrez Gene 381629
UniGene Mm.28144
RefSeq NP_997635
MGI ID
MGI Symbol Atraid
OMIM
CCDS
HPRD
IMGT
EMBL AK002276 AK151307 AK151366 AK169267 BC049637 BC057097
GenPept AAH49637 AAH57097 BAB21981 BAE30289 BAE30340 BAE41028

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca