Version 5.4
Mus musculus Protein: Whsc1
Summary
InnateDB Protein IDBP-251840.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Whsc1
Protein Name Wolf-Hirschhorn syndrome candidate 1 (human)
Synonyms 5830445G22Rik; 9430010A17Rik; AW555663; C130020C13Rik; D030027O06Rik; D930023B08Rik; mKIAA1090; MMSET; NSD2; Whsc1l;
Species Mus musculus
Ensembl Protein ENSMUSP00000110041
InnateDB Gene IDBG-154157 (Whsc1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0018024 histone-lysine N-methyltransferase activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0003149 membranous septum morphogenesis
GO:0003289 atrial septum primum morphogenesis
GO:0003290 atrial septum secundum morphogenesis
GO:0016568 chromatin modification
GO:0034968 histone lysine methylation
GO:0060348 bone development
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:1276574
InterPro IPR000313 PWWP domain
IPR009071 High mobility group box domain
PFAM PF00855
PF00505
PF09011
PRINTS
PIRSF
SMART SM00293
SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z3E0
UniProt Splice Variant
Entrez Gene 107823
UniGene Mm.490310
RefSeq NP_001171355
MGI ID
MGI Symbol Whsc1
OMIM
CCDS
HPRD
IMGT
EMBL AC162898 AC163329
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca